Robert Safirstein Selected Research

renalase

1/2022	Inhibition of renalase drives tumour rejection by promoting T cell activation.
1/2022	Kidney-Targeted Renalase Agonist Prevents Cisplatin-Induced Chronic Kidney Disease by Inhibiting Regulated Necrosis and Inflammation.
1/2022	Association of renalase with clinical outcomes in hospitalized patients with COVID-19.
1/2017	Extracellular renalase protects cells and organs by outside-in signalling.
3/2016	Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer.
1/2016	Renalase Expression by Melanoma and Tumor-Associated Macrophages Promotes Tumor Growth through a STAT3-Mediated Mechanism.
1/2015	Identification of a receptor for extracellular renalase.
9/2014	Renalase: its role as a cytokine, and an update on its association with type 1 diabetes and ischemic stroke.
6/2014	Renalase prevents AKI independent of amine oxidase activity.

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Robert Safirstein Research Topics

Disease

4	Chronic Renal Insufficiency 01/2023 - 01/2019
4	Necrosis 01/2023 - 06/2014
4	Neoplasms (Cancer) 01/2022 - 01/2016
4	Fibrosis (Cirrhosis) 01/2021 - 04/2004
3	Acute Kidney Injury (Acute Renal Failure) 01/2023 - 01/2015
3	Inflammation (Inflammations) 01/2023 - 01/2022
2	Melanoma (Melanoma, Malignant) 01/2022 - 01/2016
2	Hypertension (High Blood Pressure) 01/2021 - 06/2014
1	Albuminuria 06/2022
1	Hypoxia (Hypoxemia) 01/2022
1	COVID-19 01/2022
1	Squamous Cell Carcinoma of Head and Neck 01/2022
1	Reperfusion Injury 01/2021
1	Ureteral Obstruction 01/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 03/2016
1	Adenocarcinoma 03/2016
1	Essential Hypertension 01/2015
1	Stroke (Strokes) 01/2015
1	Cardiomegaly (Heart Hypertrophy) 01/2015
1	Ischemic Stroke 09/2014
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 09/2014

Drug/Important Bio-Agent (IBA)

9	renalaseIBA 01/2022 - 06/2014
4	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 06/2014
3	FlavoproteinsIBA 01/2022 - 01/2015
2	AntibodiesIBA 01/2022 - 03/2016
2	CytokinesIBA 01/2022 - 09/2014
2	SaltsIBA 01/2021 - 04/2004
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2019
1	AlbuminsIBA 06/2022
1	CreatinineIBA 06/2022
1	Programmed Cell Death 1 ReceptorIBA 01/2022
1	Immune Checkpoint InhibitorsIBA 01/2022
1	baojiIBA 01/2021
1	Folic Acid (Vitamin M)FDA LinkGeneric 01/2021
1	ThioredoxinsIBA 01/2021
1	Tolnaftate (Ting)IBA 01/2021
1	UromodulinIBA 01/2021
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2019
1	CollagenIBA 04/2016
1	Monoclonal AntibodiesIBA 03/2016
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2016
1	Small Interfering RNA (siRNA)IBA 03/2016
1	p38 Mitogen-Activated Protein KinasesIBA 01/2016
1	Blocking AntibodiesIBA 01/2016
1	Peptides (Polypeptides)IBA 01/2016
1	Oxidoreductases (Dehydrogenase)IBA 01/2015
1	Adenosine Triphosphatases (ATPase)IBA 01/2015
1	NucleotidesIBA 01/2015
1	CatecholaminesIBA 06/2014
1	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 06/2014
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 04/2004
1	Calcium Channels (Calcium Channel)IBA 04/2004
1	Transforming Growth Factor beta (TGF-beta)IBA 04/2004
1	RNA (Ribonucleic Acid)IBA 04/2004

Therapy/Procedure

1	Drug Therapy (Chemotherapy) 01/2022
1	Cardiopulmonary Resuscitation (CPR) 01/2022
1	Therapeutics 01/2016